Hydrogels for eye diseases

We developed an alternative to eye drops and ointment to treat eye diseases. The active ingredients they contain are often poorly absorbed or quickly degraded. Innovative electrospin fleeced, which dissolve quickly after placing on the eye and form a hydrogel, will be used. Thus, the active ingredients can have a longer  effect on theeye and are absorbed into the tear fluid leading to more efficient therapy. In addition, these hycompletelydrogels have a better shelf life and tolerability.

Icon Hydrogels for eye diseases
Portrait Mäder

Prof. Dr. Karsten Mäder

Portrait Viestenz

Prof. Dr. Arne Viestenz

Portrait Heinzelmann

Dr. Joanna Heinzelmann

Publications

Göttel B, de Souza E Silva JM, Santos de Oliveira C, Syrowatka F, Fiorentzis M, Viestenz A, Viestenz A, Mäder K. Electrospun nanofibers – A promising solid in-situ gelling alternative for ocular drug delivery. Eur J Pharm Biopharm. 2020;146:125-132. doi: 10.1016/j.ejpb.2019.11.012

Göttel B, Lucas H, Syrowatka F, Knolle W, Kuntsche J, Heinzelmann J, Viestenz A, Mäder K. In situ Gelling Amphotericin B Nanofibers: A New Option for the Treatment of Keratomycosis. Front Bioeng Biotechnol. 2020, 21;8:600384. doi: 10.3389/fbioe.2020.600384.

Patents / Awards

Hugo Junkers Prize 2023
1st prize „Innovativste Vorhaben der Grundlagenforschung
https://www.hugo-junkers-preis.de/preistraeger/preistraeger-2023

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